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And he was surprised by what he learned. Collins has a predisposition for type-2 diabetes, something he had never suspected.

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The study could lead to the development of personalized drugs that will use this trait to eliminate cancer, TAU added. In the study published in the journal Nature, TAU researchers and their colleagues from the United States, Germany, the Netherlands, and Italy, showed how an abnormal number of chromosomes aneuploidya unique characteristic of cancer cells, can become a vulnerability of these cells. This is the most common genetic change in cancer, and when it appears in cancer cells, they can advance the progression of the disease.

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In an attempt to find the ever elusive panacea for cancer, contemporary science has put forth three main paradigms that I will describe briefly. Over the last four decades, cancer has been considered principally a genetic disease and the research focus has been to characterize the nature and number of genes associated with oncogenesis. Today, it is clear that at the genetic level, each individual cancer has a unique make-up harboring idiosyncratic genetic alterations 1.

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